Use of Active Surveillance to Validate International Classification of Diseases Code Estimates of Rotavirus Hospitalizations in Children
| Autor: | Mary Allen Staat, David I. Bernstein, Nancy E. Roberts, Joseph S. Bresee, Carla Thieman, Roger I. Glass, Vincent P. Hsu, Umesh D. Parashar |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Diarrhea
Male Rotavirus Pediatrics medicine.medical_specialty Validation study viruses medicine.medical_treatment Reoviridae medicine.disease_cause Rotavirus Infections fluids and secretions International Classification of Diseases medicine Humans Ohio Patient discharge biology business.industry Infant virus diseases Length of Stay Acute gastroenteritis biology.organism_classification Patient Discharge Gastroenteritis Hospitalization El Niño Child Preschool Population Surveillance Acute Disease Pediatrics Perinatology and Child Health Female Icd codes business Watchful waiting |
| Zdroj: | Pediatrics. 115:78-82 |
| ISSN: | 1098-4275 0031-4005 |
| Popis: | Objective. National estimates of hospi- talizations for rotavirus, the leading cause of acute gas- troenteritis (AGE) in children, have been used to estab- lish the need for rotavirus vaccines. A previous method directly estimated discharges by using the rotavirus-spe- cific International Classification of Diseases (ICD) code, but this method has not been validated. Our study eval- uated the sensitivity of the rotavirus ICD code among children hospitalized for AGE by using active surveil- lance for rotavirus at a tertiary children's hospital. Design. We compared data for rotavirus-coded hospi- tal discharges in 2000-2001 at Cincinnati Children's Hos- pital Medical Center with data on laboratory-confirmed cases of rotavirus obtained from active surveillance. We estimated additional rotavirus hospitalizations by ex- trapolating the proportion of rotavirus-positive results from active-surveillance cases to those with an unknown rotavirus status. Results. Of 767 cases of AGE-related discharge codes, 103 (13%) were coded as rotavirus, 91% (94 of 103) of which were laboratory-confirmed diagnoses. Among all children discharged with an AGE-related illness, 260 (34%) were enrolled in active surveillance, of whom 155 (60%) tested positive for rotavirus. An additional 47 lab- oratory-confirmed rotavirus-case patients not enrolled in active surveillance yielded a total of 202 rotavirus cases and a maximum sensitivity of the rotavirus code of 47%. Extrapolation indicated that an additional 170 untested children might be rotavirus-positive, yielding a total of 372 rotavirus hospitalizations and a minimum sensitivity of the rotavirus code of 25%. Conclusions. Measurement of rotavirus-coded hospi- tal discharges alone seems to greatly underestimate the true burden of rotavirus-associated hospitalizations. The numbers of national rotavirus hospitalization discharges may be substantially greater than previously estimated. Pediatrics 2005;115:78-82; acute gastroenteritis, United States, child, surveillance, hospitalization, ICD codes, sensitivity, specificity. |
| Databáze: | OpenAIRE |
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