Transcatheter aortic valve replacement: transapical resection of the aortic valve in vivo
| Autor: | Monika Leester-Schaedel, Lucian Lozonschi, Georg Lutter, René Quaden |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Pulmonary and Respiratory Medicine
Aortic valve Cardiac Catheterization medicine.medical_specialty Swine medicine.medical_treatment New Ideas Intracardiac injection Extracorporeal Valve replacement Animals Medicine Ventricular outflow tract Cardiac catheterization Heart Valve Prosthesis Implantation business.industry Aortic Valve Stenosis Equipment Design medicine.disease Surgery Disease Models Animal medicine.anatomical_structure Aortic Valve Aortic valve stenosis Circulatory system cardiovascular system Cardiology and Cardiovascular Medicine business |
| Zdroj: | Interactive CardioVascular and Thoracic Surgery. 15:348-351 |
| ISSN: | 1569-9285 1569-9293 |
| Popis: | The resection of pulmonary valves has already been demonstrated in an experimental beating-heart model. The aim of this study was to analyse the transapical laser-assisted resection of aortic valves in an in vivo porcine model in a non-beating heart. The resection was performed in a porcine model (n = 10) using a Thullium:YAG laser. After establishing a standard extracorporeal circulatory support, the aortic valve isolation chamber (AVIC) system was inserted transapically. The resection of the aortic leaflets was carried out step-by-step in the arrested heart. The AVIC implantation, the resection process, and the gross anatomy of intracardiac lesions were analysed. The procedure for installing the AVIC took 5.8 ± 1.5 min. A sealed chamber was achieved in 9/10 cases. The resection of the valves was performed in 8/10 and completed in 7/10 cases. The resection took, on average, 7.4 ± 2.7 min/cusp. In 9/10 cases, the sealing was sufficient. Gross anatomy and histological analysis demonstrated only superficial damage to the surrounding tissue. In this study, the in vivo on-pump isolation of the left ventricular outflow tract and the laser resection of the native aortic valve could be demonstrated successfully. Nevertheless, this model is the next step towards a beating-heart resection of the aortic valve using the isolation chamber. |
| Databáze: | OpenAIRE |
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