Characterizing the tissue dielectric constant of skin basal cell cancer lesions
| Autor: | Harvey N. Mayrovitz, S. R. Gildenberg, L. Killpack, P. Spagna, D. A. Altman |
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| Rok vydání: | 2018 |
| Předmět: |
Male
Skin Neoplasms Future studies Dermatology Skin Diseases Diagnosis Differential Lesion 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine Body Water In vivo Skin Physiological Phenomena Electric Impedance medicine Humans Basal cell Basal cell carcinoma Aged Skin Basal Cell Carcinoma business.industry Cancer Middle Aged medicine.disease Carcinoma Basal Cell 030220 oncology & carcinogenesis Female Skin cancer medicine.symptom Nuclear medicine business |
| Zdroj: | Skin Research and Technology. 24:686-691 |
| ISSN: | 0909-752X |
| Popis: | BACKGROUND Measuring tissue dielectric constant (TDC) of cancer tissues to distinguish them from normal or non-cancerous tissues has been an active area of research that has targeted several different cancer types usually using in vitro specimens. The goal of this study was to determine if and to what extent TDC values measured in vivo at 300 MHz using a simple hand-held measuring device might differentiate between skin cancer lesions and non-cancerous skin. MATERIALS AND METHODS Triplicate TDC measurements were made in 32 patients who were subsequently diagnosed with skin basal cell carcinoma (BCC) and in 14 patients subsequently diagnosed as having non-cancerous lesions. Lesion TDC values were compared to contralateral unaffected skin and between lesion types. RESULTS A significantly lower TDC value (mean ± SD) of BCC lesions (TDCL ) vs TDC values of contralateral non-affected skin (TDCC ) was found (22.4 ± 16.2 vs 38.1 ± 15.2, P |
| Databáze: | OpenAIRE |
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