Chlamydia trachomatis serotype A infections in the Amazon region of Brazil: prevalence, entry and dissemination
| Autor: | William Botelho de Brito, Angélica Menezes Santiago, Antonio Carlos Rosário Vallinoto, Vânia Nakauth Azevedo, Marluísa de Oliveira Guimarães Ishak, Ricardo Ishak, Núbia Caroline Costa de Almeida, Maurimélia Mesquita da Costa |
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| Jazyk: | angličtina |
| Rok vydání: | 2015 |
| Předmět: |
Microbiology (medical)
Serotype medicine.medical_specialty lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Population Seroprevalence Chlamydia trachomatis Biology medicine.disease_cause Epidemiology parasitic diseases Prevalence medicine Humans Serotyping Fluorescent Antibody Technique Indirect education Epidemiologia education.field_of_study Chlamydia Infecções por Chlamydia Serotype A Sorotipo A Chlamydia Infections medicine.disease Antibodies Bacterial Virology Amazônia brasileira Infectious Diseases Trachoma Bactérias Immunoglobulin G Parasitology Pneumonia (non-human) Brazil |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Volume: 48, Issue: 2, Pages: 170-174, Published: APR 2015 Repositório Institucional da UFPA Universidade Federal do Pará (UFPA) instacron:UFPA Revista da Sociedade Brasileira de Medicina Tropical, Vol 48, Iss 2, Pp 170-174 (2015) Revista da Sociedade Brasileira de Medicina Tropical v.48 n.2 2015 Revista da Sociedade Brasileira de Medicina Tropical Sociedade Brasileira de Medicina Tropical (SBMT) instacron:SBMT |
| Popis: | INTRODUCTION: Chlamydia infection is associated with debilitating human diseases including trachoma, pneumonia, coronary heart disease and urogenital diseases. Serotypes of C. trachomatis show a fair correlation with the group of diseases they cause, and their distribution follows a well-described geographic pattern. Serotype A, a trachoma-associated strain, is known for its limited dissemination in the Middle East and Northern Africa. However, knowledge on the spread of bacteria from the genus Chlamydia as well as the distribution of serotypes in Brazil is quite limited. METHODS: Blood samples of 1,710 individuals from ten human population groups in the Amazon region of Brazil were examined for antibodies to Chlamydia using indirect immunofluorescence and microimmunofluorescence assays. RESULTS: The prevalence of antibodies to Chlamydia ranged from 23.9% (Wayana-Apalai) to 90.7% (Awa-Guaja) with a mean prevalence of 50.2%. Seroreactivity was detected to C. pneumoniae and to all serotypes of C. trachomatis tested; furthermore, we report clear evidence of the as-yet-undescribed occurrence of serotype A of C. trachomatis. CONCLUSIONS: Specific seroreactivity not only accounts for the large extent of dissemination of C. trachomatis in the Amazon region of Brazil but also shows an expanded area of occurrence of serotype A outside the epidemiological settings previously described. Furthermore, these data suggest possible routes of Chlamydia introduction into the Amazon region from the massive human migration that occurred during the 1,700s. |
| Databáze: | OpenAIRE |
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