Physical function changes in prostate cancer patients on androgen deprivation therapy: a 2-year prospective study
| Autor: | Subashan Perera, Susan L. Greenspan, Joel B. Nelson, Gijsberta J. van Londen, Cheryl A. Clay, Matthew E. Levy |
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| Rok vydání: | 2007 |
| Předmět: |
Nephrology
Male medicine.medical_specialty Time Factors Urology Physical fitness Body fat percentage Drug Administration Schedule Androgen deprivation therapy Gonadotropin-Releasing Hormone Prostate cancer Internal medicine Medicine Humans Prospective Studies Prospective cohort study Aged Aged 80 and over business.industry Cancer Prostatic Neoplasms Androgen Antagonists Middle Aged medicine.disease Endocrinology Treatment Outcome Physical Fitness Lean body mass Body Composition business Psychomotor Performance Follow-Up Studies |
| Zdroj: | Urology. 71(4) |
| ISSN: | 1527-9995 |
| Popis: | OBJECTIVES To investigate the influence of androgen deprivation therapy (ADT) in men with nonmetastatic prostate cancer. METHODS We conducted a 2-year controlled, prospective study. Twenty-three men on 6 months or longer of ADT (chronic), 12 men on less than 6 months of ADT (acute), and 13 men not on ADT (healthy controls or prostate cancer patients not on ADT) were studied. We used validated, objective tests for physical and visual-motor function and dual X-ray absorptiometry for body composition at baseline and at 24 months. RESULTS We found the baseline percentage of body fat increased and baseline percentage of lean mass decreased with duration of ADT (P |
| Databáze: | OpenAIRE |
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