Antigenic characterization of the nucleocapsid protein of Newcastle disease virus by means of a new panel of monoclonal antibodies
| Autor: | Aidyn Kydyrmanov, Daulbaeva Klara D, M. Lipkind, Marat Sayatov, E Shihmanter, C. Örvell, A. Panshin, N. Asanov, Y. Weisman |
|---|---|
| Rok vydání: | 2000 |
| Předmět: |
Paramyxoviridae
medicine.drug_class Immunology Newcastle disease virus Monoclonal antibody Antibodies Viral Microbiology Newcastle disease Binding Competitive Virus Epitope Viral Proteins Antigen Species Specificity medicine Immunology and Allergy Mononegavirales Antigens Viral General Veterinary biology Antibodies Monoclonal General Medicine Nucleocapsid Proteins biology.organism_classification Virology Molecular biology Nucleoprotein Immunoglobulin Isotypes Infectious Diseases Nucleoproteins |
| Zdroj: | Comparative immunology, microbiology and infectious diseases. 23(3) |
| ISSN: | 0147-9571 |
| Popis: | Nine monoclonal antibodies (MAB) against nucleocapsid protein (NP) of Newcastle disease virus (NDV) have been prepared and characterized. All the MABs were classified into three groups by means of the competitive binding assay. At least three antigenic sites were delineated on the NP. The 1st site includes two closely located epitopes; the 2nd site includes two related and two distinct epitopes; the 3rd site includes two closely related and one distinct epitopes. |
| Databáze: | OpenAIRE |
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