Arsenic-containing hydrocarbons are toxic in the in vivo model Drosophila melanogaster
| Autor: | Astrid Jeibmann, Tanja Schwerdtle, Jacqueline Schulz, Kevin A. Francesconi, Franziska Ebert, Mojtaba S. Taleshi, Sören Meyer |
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| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Biophysics Developmental toxicity chemistry.chemical_element In vivo toxicity Models Biological Biochemistry Arsenic Biomaterials Toxicology chemistry.chemical_compound Human health In vivo Animals Institut für Biochemie und Biologie Arsenite Life Cycle Stages Manganese biology Metals and Alloys biology.organism_classification Hydrocarbons Drosophila melanogaster chemistry Chemistry (miscellaneous) Toxicity ddc:540 Institut für Chemie Female |
| Popis: | Arsenic-containing hydrocarbons (AsHC) constitute one group of arsenolipids that have been identified in seafood. In this first in vivo toxicity study for AsHCs, we show that AsHCs exert toxic effects in Drosophila melanogaster in a concentration range similar to that of arsenite. In contrast to arsenite, however, AsHCs cause developmental toxicity in the late developmental stages of Drosophila melanogaster. This work illustrates the need for a full characterisation of the toxicity of AsHCs in experimental animals to finally assess the risk to human health related to the presence of arsenolipids in seafood. |
| Databáze: | OpenAIRE |
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