Root stem cell niche networks: it’s complexed! Insights from Arabidopsis
| Autor: | Renze Heidstra, Renan Pardal |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
0106 biological sciences
0301 basic medicine SHORT-ROOT PLETHORA Physiology WOX5 quiescent centre Cell Meristem Arabidopsis Plant Science 01 natural sciences Plant Roots JACKDAW 03 medical and health sciences Auxin Gene Expression Regulation Plant medicine Asymmetric cell division Laboratorium voor Moleculaire Biologie stem cell niche Transcription factor development Review Papers chemistry.chemical_classification biology AcademicSubjects/SCI01210 Arabidopsis Proteins food and beverages biology.organism_classification root Cell biology 030104 developmental biology medicine.anatomical_structure SCARECROW chemistry Laboratory of Molecular Biology Stem cell EPS Function (biology) 010606 plant biology & botany |
| Zdroj: | Journal of Experimental Botany Journal of Experimental Botany, 72(19), 6727-6738 Journal of Experimental Botany 72 (2021) 19 |
| ISSN: | 1460-2431 0022-0957 |
| Popis: | The presence of two meristematic cell populations in the root and shoot apex allows plants to grow indefinitely. Due to its simple and predictable tissue organization, the Arabidopsis root apical meristem remains an ideal model to study mechanisms such as stem cell specification, asymmetric cell division, and differentiation in plants. The root stem cell niche consists of a quiescent organizing centre surrounded by mitotically active stem cells, which originate all root tissues. The transcription factors PLETHORA, SCARECROW, and WOX5 form signalling hubs that integrate multiple inputs from an increasing number of proteins implicated in the regulation of stem cell niche function. Recently, locally produced auxin was added to the list of important mobile factors in the stem cell niche. In addition, protein–protein interaction data elegantly demonstrate how parallel pathways can meet in a common objective. Here we discuss how multiple networks converge to specify and maintain the root stem cell niche. An updated overview of the main gene networks converging for the specification and maintenance of the Arabidopsis root stem cell niche. |
| Databáze: | OpenAIRE |
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