Supplementary Figure S6 from Integration of Downstream Signals of Insulin-like Growth Factor-1 Receptor by Endoplasmic Reticulum Stress for Estrogen-Induced Growth or Apoptosis in Breast Cancer Cells
| Autor: | V. Craig Jordan, Megan L. Russell, Pilar Ramos, Xiaojun Zou, Russell E. McDaniel, Fadeke A. Agboke, Philipp Y. Maximov, Heather E. Cunliffe, Ping Fan |
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| Rok vydání: | 2023 |
| DOI: | 10.1158/1541-7786.22514944 |
| Popis: | MCF-7:5C cells were transfected with scrambled, PERK (A), IRE1α (B), and ATF6 (C) siRNAs for 72 hours. Then, cells were treated with vehicle (0.1% EtOH; con) or E2 (10-9 mol/L) for 72 hours. Annexin V binding assay was used to detect apoptosis. (D). Cell lysates were harvested after transfected with scrambled, PERK, IRE1α, and ATF6 siRNAs for 72 hours. IGF-1R levels were detected through Western blot. β-actin was measured as loading control. |
| Databáze: | OpenAIRE |
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