Muscular dystrophy in a patient with multiple sclerosis. Another 'double-trouble'?
| Autor: | Dimitrios Parissis, Christos Bakirtzis, D. Karacostas, Nikolaos Grigoriadis, Panagiotis Ioannidis |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
musculoskeletal diseases congenital hereditary and neonatal diseases and abnormalities Multiple Sclerosis Population Bioinformatics Pathogenesis medicine Humans Facioscapulohumeral muscular dystrophy Muscular dystrophy education education.field_of_study business.industry Multiple sclerosis Brain Dystrophy General Medicine medicine.disease Magnetic Resonance Imaging Muscular Dystrophy Facioscapulohumeral nervous system diseases Spinal Cord Neurology Immunological Factors Disease Progression Female Neurology (clinical) business Follow-Up Studies |
| Zdroj: | Multiple Sclerosis and Related Disorders. 4:342-344 |
| ISSN: | 2211-0348 |
| DOI: | 10.1016/j.msard.2015.06.007 |
| Popis: | Facioscapulohumeral muscular dystrophy (FSHD) is considered a relatively common muscular dystrophy affecting approximately 1:15,000 individuals in the general population. Single case reports have described the rare co-occurrence of FSHD with other hereditary neuromuscular disorders, leading to atypical phenotypes. We report herein the case of a 26-year-old woman with genetically proven FSHD, who additionally developed otherwise typical multiple sclerosis (MS). Although there is no direct relationship between FSHD and MS, they might, nevertheless, share some common pathophysiological mechanisms, as recent research suggests. In particular, we comment on the potential, but not yet proven, role of immunological factors in the pathogenesis of FSHD. |
| Databáze: | OpenAIRE |
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