Human health risks and benefits assessment based on OCPs, PCBs, toxic elements and fatty acids in the pelagic fish species from the Adriatic Sea
| Autor: | Tijana Milićević, Dubravka Relić, Jasna Đinović-Stojanović, Snježana Herceg Romanić, Bosiljka Mustać, Aleksandar Popović, Gordana Jovanović |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
Benefit-risk
Environmental Engineering Toxic pollutants Health Toxicology and Mutagenesis chemistry.chemical_element Non-carcinogenic risk and carcinogenic risk 010501 environmental sciences Risk Assessment 01 natural sciences Gas Chromatography-Mass Spectrometry Specific risks Chub mackerel Round sardinella Anchovy Hydrocarbons Chlorinated Animals Humans Environmental Chemistry Ingestion 14. Life underwater Food science Pesticides Fatty acids Arsenic 0105 earth and related environmental sciences chemistry.chemical_classification biology Fatty Acids 010401 analytical chemistry Public Health Environmental and Occupational Health Fatty acid Pelagic zone General Medicine General Chemistry biology.organism_classification Polychlorinated Biphenyls Pollution Horse mackerel 0104 chemical sciences 3. Good health Fish chemistry 13. Climate action |
| Zdroj: | Chemosphere |
| Popis: | Benefits and risks of the fish consumption should be assessed to balance the ingestion of healthy omega-3 fatty acids and adverse chemicals. Persistent organic pollutants-POPs (organochlorine pesticides-OCPs and polychlorinated biphenyls-PCB), macro- and micro-elements and fatty acid contents were determined in six fish species from the Adriatic Sea to assess health risks for consumers (worst-case scenario, diseases development risks and benefit-risk). 16 element, 24 POPs and 14 fatty acid contents were determined in six pelagic species which can be used in human diet. Element concentrations were determined by inductively coupled plasma mass spectrometry (ICP-MS), POPs by high-resolution gas chromatography and fatty acid content by gas–liquid chromatography. Diet based on chub mackerel and round sardinella showed lower daily intake (DI) of POPs and highest DI of essential omega-3 fatty acids than other investigated species. Lower ingestion of toxic elements can be observed by consuming anchovy and round sardinella. Based on POP concentrations, there was not observed non-carcinogenic (HI) nor carcinogenic (CR) risks for consumers. Based on element concentrations, there was low HI (0.1 ≥ HI ≥ 1), while the maximum HIs and outlier values (horse mackerel and anchovy samples) implied the presence of HI (HI > 1). The most significant contributor to total non-carcinogenic and carcinogenic risks was inorganic arsenic (inorganic As). Acceptable CR for consumers was assessed, but maximum CR for consumers of horse mackerel and anchovy (CR ≥ 1 × 10–6) showed adverse effects on human health. There were low HIs for developing cardiovascular, nervous, and reproductive diseases, and maximum HIs were higher than 1. Acceptable (1 × 10−4≥CR ≥ 1 × 10−6) risks were observed for developing cancer of nervous system and reproductive organs. Among investigated fish samples, those with higher ƩBR (benefit-risks) and BR for arsenic (As) than median value have a higher risk than benefits in the human diet. Supplementary material: [https://cherry.chem.bg.ac.rs/handle/123456789/4665] |
| Databáze: | OpenAIRE |
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