| Autor: |
Lucia Sabová, Ivana Cingeľová Maruščáková, Simona Koleničová, Dagmar Mudroňová, Beata Holečková, Rastislav Sabo, Anna Sobeková, Tomáš Majchrák, Marek Ratvaj |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
Environmental toxicology and pharmacology. 92 |
| ISSN: |
1872-7077 |
| Popis: |
Currently several pyrethroids (e.g., flumethrin and tau-fluvalinate) are used in apiculture worldwide as acaricides/miticides. The long half-lives of pyrethroids in synthetic acaricides applied to hive matrices, may adversely affect the health of bee colony. The potentially adverse effects of synthetic acaricide/miticide tau-fluvalinate (tech.) on winter honeybees were assessed in this study (OECD 245 2017). No dose-dependent mortality in in vitro reared winter honeybees was observed after chronic oral 10-day exposure to syrup (50% w/v) spiked with a maximum concentration of 750 μg a.i./kg diet and its 1/10 concentration. The No Observed Effect Concentration is ≥ 750 μg a.i./kg diet. Tau-fluvalinate testing for the sublethal effects on bee immune system showed up-regulated gene expression encoding abaecin, lysozyme, and defensin in both tested groups, however the expression of hymenoptaecin gene was reduced. Moreover, tau-fluvalinate significantly induced levels of DNA damage in exposed bees, which can result in adverse genotoxic effect. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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