Blood volume measurement with indocyanine green pulse spectrophotometry: dose and site of dye administration
| Autor: | Koos A. H. Zwinderman, Leonard J. van Boven, Menno R. Germans, Gerrit J. Bouma, Philip C. De Witt Hamer |
|---|---|
| Přispěvatelé: | Neurosurgery, CCA - Disease profiling, Amsterdam Neuroscience, Amsterdam Public Health, Epidemiology and Data Science, Faculteit der Geneeskunde |
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Adult
Indocyanine Green Male Subarachnoid hemorrhage Drug-Related Side Effects and Adverse Reactions Clinical Neurology Hemodynamics Blood volume Triple H Catheterization chemistry.chemical_compound Predictive Value of Tests Spectrophotometry medicine Humans Coloring Agents Aged Blood Volume Clinical Article medicine.diagnostic_test Blood Volume Determination Dose-Response Relationship Drug Pulse (signal processing) business.industry Middle Aged Subarachnoid Hemorrhage medicine.disease chemistry Anesthesia Blood volume measurement Injections Intravenous Pulse densitometry Surgery Female Neurology (clinical) business Nuclear medicine Densitometry Indocyanine green |
| Zdroj: | Germans, M R, Verselewel de Witt Hamer, P C, van Boven, L J, Zwinderman, K & Bouma, G J 2010, ' Blood volume measurement with indocyanine green pulse spectrophotometry: dose and site of dye administration ', Acta Neurochirurgica, vol. 152, no. 2, pp. 251-255 . https://doi.org/10.1007/s00701-009-0501-4 Acta Neurochirurgica Acta Neurochirurgica, 152(2), 251-255. Springer Wien Acta neurochirurgica, 152(2), 251-5; discussion 255. Springer Wien Acta neurochirurgica, 152(2), 251-255. Springer Wien |
| ISSN: | 0001-6268 |
| Popis: | Background (1) To determine the optimal administration site and dose of indocyanine green (ICG) for blood volume measurement using pulse spectrophotometry, (2) to assess the variation in repeated blood volume measurements for patients after subarachnoid hemorrhage and (3) to evaluate the safety and efficacy of this technique in patients who were treated for an intracranial aneurysm. Methods Four repeated measurements of blood volume (BV) were performed in random order of bolus dose (10 mg or 25 mg ICG) and venous administration site (peripheral or central) in eight patients admitted for treatment of an intracranial aneurysm. Another five patients with subarachnoid hemorrhage underwent three repeated BV measurements with 25 mg ICG at the same administration site to assess the coefficient of variation. Findings The mean ± SD in BV was 4.38 ± 0.88 l (n = 25) and 4.69 ± 1.11 l (n = 26) for 10 mg and 25 mg ICG, respectively. The mean ± SD in BV was 4.59 ± 1.15 l (n = 26) and 4.48 ± 0.86 l (n = 25) for central and peripheral administration, respectively. No significant difference was found. The coefficient of variance of BV measurement with 25 mg of ICG was 7.5% (95% CI: 3–12%). Conclusions There is no significant difference between intravenous administration of either 10 or 25 mg ICG, and this can be injected through either a peripheral or central venous catheter. The 7.5% coefficient of variation in BV measurements determines the detectable differences using ICG pulse spectrophotometry. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink