Does early pulmonary rehabilitation reduce acute health-care utilization in COPD patients admitted with an exacerbation? A randomized controlled study
Autor: | John Kolbe, Wendy Fergusson, Lisa Moodie, Nichola Good, Fiona O'kane, Leanne Rhodes, Pam Young, Irene Zeng, Tam Eaton, Phillippa Poole |
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Rok vydání: | 2009 |
Předmět: |
Pulmonary and Respiratory Medicine
Male medicine.medical_specialty Exacerbation medicine.medical_treatment Patient Readmission Pulmonary function testing law.invention Pulmonary Disease Chronic Obstructive Quality of life Randomized controlled trial law Internal medicine Outcome Assessment Health Care Outpatients medicine Humans Pulmonary rehabilitation Prospective Studies Prospective cohort study Aged Aged 80 and over COPD Inpatients Rehabilitation business.industry Health Care Costs Middle Aged medicine.disease Physical therapy Disease Progression Quality of Life Female business Delivery of Health Care New Zealand |
Zdroj: | Respirology (Carlton, Vic.). 14(2) |
ISSN: | 1440-1843 |
Popis: | Background and objective: In COPD, hospital admissions and readmissions account for the majority of health-care costs. The aim of this prospective randomized controlled study was to determine if early pulmonary rehabilitation, commenced as an inpatient and continued after discharge, reduced acute health-care utilization. Methods: Consecutive COPD patients (n = 397), admitted with an exacerbation, were screened: 228 satisfied the eligibility criteria, of whom 97 consented to randomization to rehabilitation or usual care. Both intention-to-treat and per-protocol analyses are reported with adherence being defined a priori as participation in at least 75% of rehabilitation sessions. Results: The participants were elderly with severe impairment of pulmonary function, poor health-related quality of life and high COPD-related morbidity. The rehabilitation group demonstrated a 23% (95% CI: 11–36%) risk of readmission at 3 months, with attendees having a 16% (95% CI: 0–32%) risk compared with 32% (95% CI: 19–45%) for usual care. These differences were not significant. There were a total of 79 COPD-related readmission days (1.7 per patient, 95% CI: 0.6–2.7, P = 0.19) in the rehabilitation group, compared with 25 (1.3 per patient, 95% CI: 0–3.1, P = 0.17) for the attendees and 209 (4.2 per patient, 95% CI: 1.7–6.7) for usual care. The BMI, airflow obstruction, dyspnoea and exercise capacity index showed a non-significant trend to greater improvement among attendees compared with those receiving usual care (5.5 (2.3) and 5.6 (2.7) at baseline, improving to 3.7 (1.9) and 4.5 (2.5), respectively, at 3 months). No adverse effects were identified. Conclusions: Early inpatient–outpatient rehabilitation for COPD patients admitted with an exacerbation was feasible and safe, and was associated with a non-significant trend towards reduced acute health-care utilization. |
Databáze: | OpenAIRE |
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