Feasibility and Potential Benefits of an Exercise Intervention in a Male With Down Syndrome Undergoing High-Dose Chemotherapy for Acute Lymphoblastic Leukemia: A Case Report
| Autor: | Max Oberste, Thomas Abel, Thomas Elter, Florian Wolf, Wilhelm Bloch, Philipp Zimmer, Michael Hallek, Linda Bühl |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Adult
Male medicine.medical_specialty Down syndrome medicine.medical_treatment Lymphoblastic Leukemia physical activity lcsh:RC254-282 03 medical and health sciences Young Adult 0302 clinical medicine Case Studies Internal medicine medicine cancer Humans Adverse effect Chemotherapy Exercise intervention exercise business.industry leukemia Cancer 030229 sport sciences Precursor Cell Lymphoblastic Leukemia-Lymphoma lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens medicine.disease Exercise Therapy Clinical trial Leukemia Complementary and alternative medicine Oncology 030220 oncology & carcinogenesis Feasibility Studies fatigue business |
| Zdroj: | Integrative Cancer Therapies Integrative Cancer Therapies, Vol 18 (2019) |
| ISSN: | 1552-695X 1534-7354 |
| Popis: | In patients with hematological malignancies, exercise is studied as a supportive measure with potential benefits on therapy and disease-related side effects. However, clinical trials have not yet integrated people with Down syndrome (DS), although this disability is associated with an increased risk for hematological malignancies. Therefore, we examined safety and feasibility of a mixed-modality exercise intervention in a male with DS undergoing high-dose chemotherapy for acute lymphoblastic leukemia. Furthermore, physical capacity and fatigue were assessed. Exercise sessions took place 3 times/wk over a 5-week period. Adherence to the exercise program was 100%, and no serious adverse events occurred. In contrast to the training sessions, applied endurance testing was not feasible. Furthermore, maintenance of fatigue level was observed. In conclusion, cancer patients with DS suffering from leukemia should not be excluded from physical activity or exercise programs. |
| Databáze: | OpenAIRE |
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