The problem of latency in the development of tumors following exposure to nickel compounds
| Autor: | G D Lumb, F W Sunderman |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Oncology
medicine.medical_specialty Time Factors Environmental Engineering Chemistry Environmental Exposure Neoplasms Experimental Pollution Rats Inbred F344 Tumor formation Rats Surgery Human tumor Nickel Nickel compounds Internal medicine medicine Animals Environmental Chemistry Animal studies Rats Wistar Latency (engineering) Delayed toxicity Waste Management and Disposal |
| Zdroj: | Science of The Total Environment. 148:185-190 |
| ISSN: | 0048-9697 |
| DOI: | 10.1016/0048-9697(94)90395-6 |
| Popis: | Six previously published animal studies of tumor production have been reviewed, in order to relate time interval between exposure to nickel and development of tumor formation. Biopsies at intervals before final tumor formation, in some of these experiments, were reviewed to define interim changes between exposure and tumor diagnosis. Correlation between rat and human life span was used to suggest a latency of human tumor expectancy following exposure to nickel. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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