Radiofrequency-induced heating versus mechanical stapler for pancreatic stump closure: in vivo comparative study
| Autor: | Enrique Berjano, Dimitri Dorcaratto, Fernando Burdío, Marta Cáceres, Ignasi Poves, Rita Quesada, Lourdes Hernández, Xavier Moll, Anna Andaluz, Luis Grande |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: |
Cancer Research
medicine.medical_specialty Hot Temperature Swine Physiology medicine.medical_treatment Catheter ablation 030230 surgery Anastomosis Radiofrequency-assisted resection TECNOLOGIA ELECTRONICA Pancreatic Fistula 03 medical and health sciences Postoperative Complications Surgical Staplers 0302 clinical medicine Atrophy Pancreatectomy Mechanical stapler In vivo Physiology (medical) medicine Animals Laparoscopy Pancreas medicine.diagnostic_test business.industry Stump closure medicine.disease Surgery surgical procedures operative medicine.anatomical_structure Pancreatic fistula 030220 oncology & carcinogenesis Duct sealing Catheter Ablation business |
| Zdroj: | RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia instname Dipòsit Digital de Documents de la UAB Universitat Autònoma de Barcelona |
| Popis: | Purpose: To assess the capacity of two methods of surgical pancreatic stump closure in terms of reducing the risk of pancreatic fistula formation (POPF): radiofrequencyinduced heating versus mechanical stapler. Materials and Methods: Sixteen pigs underwent a laparoscopic transection of the neck of the pancreas. Pancreatic anastomosis was always avoided in order to work with an experimental model prone to pancreatic fistula formation (POPF). Pancreatic stump closure was conducted either by stapler (ST Group, n=8) or radiofrequency energy (RF Group, n=8). Both groups were compared for incidence of POPF and histopathologic alterations of the pancreatic remnant. Results: Six animals (75%) in the ST Group and one (14%) in the RF Group were diagnosed of POPF (p=0.019). One animal in the RF Group and three animals in the ST Group had a pseudocyst in close contact with both pancreas stumps. On day 30 postoperative, almost complete atrophy of the exocrine distal pancreas was observed when the main pancreatic duct was efficiently sealed. Conclusions: Our findings suggest that RF-induced heating is more effective at closing the pancreatic stump than mechanical stapler and leads to the complete atrophy of the distal remnant pancreas. This work was supported by the Spanish 'Programa Estatal de Investigacion, Desarrollo e Innovacion Orientada a los Retos de la Sociedad' under grant TEC2014-52383-C3-R (TEC2014-52383-C3-3-R). F.B., R.Q. and E.B. declare stock ownership in Apeiron Medical S.L., a company that has a license for the patent US 8.303.584.B2, on which the device tested in this study is based. The other authors report no conflict of interests or financial ties to disclose. The authors alone are responsible for the content and writing of the paper. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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