Synthesis of Phosphaisocoumarins through Rhodium-Catalyzed Cyclization Using Alkynes and Arylphosphonic Acid Monoesters

Autor:	Jungmin Seo, Phil Ho Lee, Youngchul Park, Sangjune Park, Incheol Jeon, Taekyu Ryu
Rok vydání:	2013
Předmět:	chemistry.chemical_compound Chemistry Organic Chemistry Functional group chemistry.chemical_element Regioselectivity Physical and Theoretical Chemistry Biochemistry Medicinal chemistry Catalysis Rhodium
Zdroj:	Organic Letters. 15:3358-3361
ISSN:	1523-7052 1523-7060
DOI:	10.1021/ol401407v
Popis:	A rhodium-catalyzed cyclization using alkynes and arylphosphonic acid monoesters for the synthesis of phosphaisocoumarins is reported. A number of arylphosphonic acid monoesters were selectively cyclized in high yields with functional group tolerance. In addition, unsymmetrical alkynes are applied in high regioselectivity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d54531a32f4ad926037cdb043b9b5d9 https://doi.org/10.1021/ol401407v Zobrazit plný text záznamu