The Efficiency of Bioapifit® Wound Care Ointment in the Treatment of Diabetic Foot Ulcers
| Autor: | Zrinka Mihalic, Štefica Findri Guštek, Višnja Oreščanin, Josipa Rodic |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: | |
| Zdroj: | Volume: 2, Issue: 2 133-137 Current Perspectives on Medicinal and Aromatic Plants (CUPMAP) |
| ISSN: | 2619-9645 2667-5722 |
| Popis: | Objective/Purpose: The objective of this study was efficacy and safety assessment of Bioapifit® wound care ointment consisted of honey, Cera flava, glycerin, the oil macerates of astringent and soothing herbs combined with essential oils for the treatment of diabetic neuropathic foot ulcers of grade II. Materials and methods: 50 patients with Wagner grade II diabetic foot ulcers were randomized into experimental and control group (25 patients each). The experimental group was treated 28 days with Bioapifit® wound care ointment applied on the wound after cleaning with povidone iodine once a day and covered with sterile gauze and bandage during the whole course of the study. The control group wounds were cleaned with povidone iodine once a day and covered with sterile gauze and bandage during the whole course of the study without further treatment. The ulcers surface area was measured at baseline and after 14 and 28 days of the treatment. Results: In the end of the treatment the mean values and standard deviation of the surface area in the experimental group dropped from 8.27±6.1 cm 2 to 0.74±0.21 cm 2 for males and from 9.01±5.9 cm 2 to 0.81±0.11 cm 2 for females. Slight, insignificant decrease was also observed in the control population (up to 25%). No side-effects were observed during the course of the study. Conclusion/Discussion: Four weeks treatment with Bioapifit® wound care ointment resulted in complete wound closure in 84% of the patients and 91% reduction in the wound surface area in the rest of them. |
| Databáze: | OpenAIRE |
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