Antibiotic Practices and Resistance in Genocide Areas of Darfur and Southern Sudan
| Autor: | Vladimir Krcmery, S. Njambi |
|---|---|
| Rok vydání: | 2008 |
| Předmět: |
Doxycycline
Microbiology (medical) Veterinary medicine business.industry Tetracycline medicine.drug_class Antibiotics General Medicine social sciences Antimicrobial humanities Vaccination Penicillin Antibiotic resistance Infectious Diseases Environmental protection Ampicillin medicine population characteristics business health care economics and organizations medicine.drug |
| Zdroj: | International Journal of Infectious Diseases. 12 |
| ISSN: | 1201-9712 |
| DOI: | 10.1016/j.ijid.2008.05.117 |
| Popis: | Background: Due to 21 years of civil war in southern Sudan and 5 years conflict of Darfur, health care infrastructure in southern and western Sudan was destroyed. St. Elizabeth University Tropical programmes involve 2 hospitals in South Darfur (Nyamlell, Gordim) and 2 in Bahr Al-Gazal in southern Sudan (Mapuordit, Marialou), with patient flow of 35.000 a year. Antibiotic policy is based on WHO guidelines in those hospitals but no community health service is available yet and vaccination was sporadic or none. Methods: On the market 4 antimicrobial drugs are available as OTC Doxycyclin, Ampicillin, Cotrimoxazole and Cloroquine. We have tested 400 isolates from patients from this area as of antibiotic free environment. Results: All isolates of Str. pneumoniae were Penicillin susceptible, all S. aureus Oxacillin susceptible and all S. pyogenes Erytromycine susceptible. All H. influenzae isolates were susceptible to Ampicillin and all E. coli to Ciprofloxacine, all but one to Cotrimoxazole. Tetracycline resistance vice versa in S. aureus and Streptococcus spp. isolates was up to 33%. Conclusion: Antimicrobial resistance in respiratory pathogens is extremly low due to lack of antibiotics because of isolation during civil war. Tetracycline resistance is high because Doxycycline is extremely cheap and available. |
| Databáze: | OpenAIRE |
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