Effects of perinatal alcohol exposure and dietary calcium supplements on skeletal and dental growth in rats
| Autor: | A.B. Taylor, M.I. Siegel, M.P. Mooney, Alphonse Riesenfeld, J.T. Seroky |
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| Rok vydání: | 1991 |
| Předmět: |
Male
medicine.medical_specialty Histology Alcohol Drinking Osteoporosis chemistry.chemical_element Alcohol Alcohol exposure Calcium chemistry.chemical_compound Sex Factors Pregnancy Internal medicine medicine Animals Dietary calcium Bone growth Analysis of Variance Bone Development business.industry medicine.disease Skeleton (computer programming) Rats Inbred F344 Rats Calcium Dietary Bone Diseases Metabolic Endocrinology chemistry Prenatal Exposure Delayed Effects Toxicity Female Anatomy business Tooth |
| Zdroj: | Acta anatomica. 140(1) |
| ISSN: | 0001-5180 |
| Popis: | Osteoporosis, hypocalcemia and skeletal size reduction are all common correlates of perinatal alcohol exposure. The present study assesses the effects of dietary calcium supplements on reversing perinatal alcohol-induced osteopenia. One hundred and twenty-nine offspring from Fisher 344 rats received 14% v/v alcohol in tap water from conception to weaning or 3 months of age followed by dietary calcium supplements (230 mg/kg/day) to 6 months of age. Significant group effects (p < 0.001) were noted for all 12 dental and skeletal dimensions measured. Results suggest that calcium therapy following perinatal alcohol exposure may ameliorate alcohol-induced osteopenia in exposed offspring. |
| Databáze: | OpenAIRE |
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