The biotransformation of t -butylacetonitrile and its boron-containing analogue trimethylamine-cyanoborane by Brevibacterium R312
| Autor: | Christopher J. Knowles, Anthony J. Millais, John A Lovelady, Andrea M. Nicholson, Duncan Casson |
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| Rok vydání: | 1997 |
| Předmět: |
Boron Compounds
Brevibacteriaceae Acetonitriles Nitrile Carboxylic acid Biochemistry Microbiology Amidase chemistry.chemical_compound Biotransformation Nitrile hydratase Amide Nitriles Genetics Brevibacterium Organic chemistry Molecular Biology chemistry.chemical_classification biology Chemistry General Medicine biology.organism_classification Butyrates Butyric Acid |
| Zdroj: | Archives of Microbiology. 168:164-168 |
| ISSN: | 1432-072X 0302-8933 |
| DOI: | 10.1007/s002030050483 |
| Popis: | The ability of the nitrile hydratase/amidase system from Brevibacterium R312 to biotransform tert-butylacetonitrile was studied with a view to their utilisation in the production of novel amino acids from isostructural compounds. Brevibacterium R312 was able to transform nitriles with this structure; however, the wide spectrum amidase from this organism was unable to biotransform the corresponding amide to the carboxylic acid. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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