Evaluation of the hemogram of Oryctolagus cuniculus envenomus

Autor: N’guessan Emmanuel Assemian, Kouadio Bernard Allali, Obou Constantin Okou, Allico Joseph Djaman, Guy Childeric Bingo
Jazyk: angličtina
Rok vydání: 2020
Předmět:
DOI: 10.5281/zenodo.4308265
Popis: The overall objective of this study was to evaluate the hemolysing action ofNaja nigricollisvenom on rabbit blood. To carry out this study, three batches of three rabbits were formed with two control batches and one experimental batch. Each control lot is composed of three rabbits (males or females) while the experimental lot is composed of two males and one female. Each rabbit from the control lots was separately collected in the purple tube (EDTA) and transported to the laboratory for analysis. The rabbits from the experimental batch were also collected distinctly a few minutes after the injection of the venom ofNaja nigricollisfor the analysis of haematological parameters. However, before the analysis of the hematological parameters of the rabbits from the control and experimental batches, anin vitrohemolysis test ofNaja nigricollisvenom was performed to verify its hemolysing power. The results showed thatNaja nigricollisvenom has a dose-dependentin vitrohemolysing power. As for the haemogram, it revealed that the venom ofNaja nigricollishas a decreasing effect on blood cells (red and white blood cells), on haemoglobin and on haematocrit, and an elevation on MGVs thus promoting anaemia.
Databáze: OpenAIRE