Daily Bathing with Chlorhexidine-Based Soap and the Prevention of Staphylococcus aureus Transmission and Infection
| Autor: | James Morley, Marin H. Kollef, Craig M. Coopersmith, Victoria J. Fraser, Melissa A Viray, David K. Warren |
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| Rok vydání: | 2014 |
| Předmět: |
Methicillin-Resistant Staphylococcus aureus
0301 basic medicine Microbiology (medical) medicine.medical_specialty Bathing Epidemiology 030106 microbiology medicine.disease_cause Staphylococcal infections Article law.invention 03 medical and health sciences 0302 clinical medicine law Internal medicine medicine Humans Infection control Prospective Studies 030212 general & internal medicine Intensive care medicine Cross Infection Transmission (medicine) business.industry Chlorhexidine Staphylococcal Infections medicine.disease Methicillin-resistant Staphylococcus aureus Intensive care unit Disinfection Intensive Care Units Infectious Diseases Staphylococcus aureus business Disinfectants medicine.drug |
| Zdroj: | Infection Control & Hospital Epidemiology. 35:243-250 |
| ISSN: | 1559-6834 0899-823X |
| DOI: | 10.1086/675292 |
| Popis: | Objective.Determine whether daily bathing with chlorhexidine-based soap decreased methicillin-resistant Staphylococcus aureus (MRSA) transmission and intensive care unit (ICU)-acquired S. aureus infection among ICU patients.Design.Prospective pre-post-intervention study with control unit.Setting.A 1,250-bed tertiary care teaching hospital.Patients.Medical and surgical ICU patients.Methods.Active surveillance for MRSA colonization was performed in both ICUs. In June 2005, a chlorhexidine bathing protocol was implemented in the surgical ICU. Changes in S. aureus transmission and infection rate before and after implementation were analyzed using time-series methodology.Results.The intervention unit had a 20.68% decrease in MRSA acquisition after institution of the bathing protocol (12.64 cases per 1,000 patient-days at risk before the intervention vs 10.03 cases per 1,000 patient-days at risk after the intervention; β, −2.62 [95% confidence interval (CI), −5.19 to −0.04]; P = .046). There was no significant change in MRSA acquisition in the control ICU during the study period (10.97 cases per 1,000 patient-days at risk before June 2005 vs 11.33 cases per 1,000 patient-days at risk after June 2005; β, −11.10 [95% CI, −37.40 to 15.19]; P = .40). There was a 20.77% decrease in all S. aureus (including MRSA) acquisition in the intervention ICU from 2002 through 2007 (19.73 cases per 1,000 patient-days at risk before the intervention to 15.63 cases per 1,000 patient-days at risk after the intervention [95% CI, −7.25 to −0.95]; P = .012)]. The incidence of ICU-acquired MRSA infections decreased by 41.37% in the intervention ICU (1.96 infections per 1,000 patient-days at risk before the intervention vs 1.15 infections per 1,000 patient-days at risk after the intervention; P = .001).Conclusions.Institution of daily chlorhexidine bathing in an ICU resulted in a decrease in the transmission of S. aureus, including MRSA. These data support the use of routine daily chlorhexidine baths to decrease rates of S. aureus transmission and infection. |
| Databáze: | OpenAIRE |
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