Factors associated with abandonment of therapy by children diagnosed with solid tumors in Peru
| Autor: | Fanny Tarrillo, Nuria Rossell, Liliana Vasquez, Sharon Chavez, Juan Antonio García, Monica Oscanoa, Ivan Maza, Rosdali Diaz, Eddy Hernandez, Jenny Geronimo |
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| Rok vydání: | 2017 |
| Předmět: |
Male
Pediatrics medicine.medical_specialty Adolescent Childhood cancer Developing country Logistic regression Treatment Refusal 03 medical and health sciences 0302 clinical medicine Neoplasms Peru Prevalence Medicine Humans Child Developing Countries Retrospective Studies business.industry Paediatric oncology Incidence (epidemiology) Infant Newborn Cancer Infant Hematology Odds ratio medicine.disease Prognosis humanities Oncology Socioeconomic Factors 030220 oncology & carcinogenesis Child Preschool Pediatrics Perinatology and Child Health Abandonment (emotional) Patient Compliance Female business 030215 immunology Follow-Up Studies |
| Zdroj: | Pediatric bloodcancer. 65(6) |
| ISSN: | 1545-5017 |
| Popis: | BACKGROUND Abandonment of treatment is a major cause of treatment failure and poor survival in children with cancer in low- and middle-income countries. The incidence of treatment abandonment in Peru has not been reported. The aim of this study was to examine the prevalence of and factors associated with treatment abandonment by pediatric patients with solid tumors in Peru. METHODS We retrospectively reviewed the sociodemographic and clinical data of children referred between January 2012 and December 2014 to the two main tertiary centers for childhood cancer in Peru. The definition of treatment abandonment followed the International Society of Paediatric Oncology, Paediatric Oncology in Developing Countries, Abandonment of Treatment recommendation. RESULTS Data from 1135 children diagnosed with malignant solid tumors were analyzed, of which 209 (18.4%) abandoned treatment. Bivariate logistic regression analysis showed significantly higher abandonment rates in children living outside the capital city, Lima (forest; odds ratio [OR] 3.25; P |
| Databáze: | OpenAIRE |
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