Symptom-oriented clinical detection versus routine imaging as a monitoring policy of relapse in patients with diffuse large B-cell lymphoma
Autor: | Jinny Park, Eun Kyung Cho, Junshik Hong, Sanghui Park, Jae Hoon Lee, Dong Bok Shin, Ji Hyun Kim, Sun Jin Sym, Hee Kyung Ahn, Kyoung Hwa Lee |
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Rok vydání: | 2014 |
Předmět: |
Adult
Diagnostic Imaging Male Cancer Research medicine.medical_specialty Young Adult Internal medicine Outpatients Ambulatory Care medicine Medical imaging Humans Outpatient clinic In patient Neoplasm Metastasis Aged Neoplasm Staging Aged 80 and over business.industry Complete remission Hematology Middle Aged Disease monitoring medicine.disease Surgery Oncology Positron-Emission Tomography Female Rituximab Lymphoma Large B-Cell Diffuse Neoplasm Recurrence Local Tomography X-Ray Computed business Diffuse large B-cell lymphoma After treatment medicine.drug |
Zdroj: | Leukemia & Lymphoma. 55:2312-2318 |
ISSN: | 1029-2403 1042-8194 |
Popis: | This study aimed at evaluating the role of routine imaging versus symptom-directed unplanned early outpatient department (OPD) visits in patients with diffuse large B-cell lymphoma (DLBCL) in complete remission (CR) by analyzing the patterns and outcomes of OPD visits for disease monitoring. Patients with DLBCL in CR after treatment in the rituximab era with any OPD monitoring visit were analyzed. A total of 856 OPD visits were recorded: 501 visits were with routine imaging, 322 were without routine imaging and 33 visits (3.9%) were unplanned early visits due to abnormal symptoms. Of the 106 analyzed patients, 15 experienced a relapse (median follow-up duration of 38.1 months). Routine imaging showed an unsatisfactory positive predictive value due to frequent false-positive visits, and a substantial number of patients with false-positive imaging underwent unnecessary biopsies or additional scans. Compared with planned OPD visits, unplanned early visits were highly related to relapse. |
Databáze: | OpenAIRE |
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