Early hematoma retraction in intracerebral hemorrhage is uncommon and does not predict outcome

Autor: Ashfaq Shuaib, Derek Emery, Jayme C. Kosior, Ana C Klahr, Brian Buck, Mahesh Kate, Kenneth Butcher
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Male
lcsh:Medicine
030204 cardiovascular system & hematology
Pathology and Laboratory Medicine
Vascular Medicine
Biochemistry
Diagnostic Radiology
0302 clinical medicine
Mathematical and Statistical Techniques
Interquartile range
Modified Rankin Scale
Edema
Odds Ratio
Medicine and Health Sciences
lcsh:Science
Stroke
Tomography
Aged
80 and over
Hematoma
Multidisciplinary
Radiology and Imaging
Statistics
Brain
Hematology
Middle Aged
Prognosis
Treatment Outcome
Neurology
Anesthesia
Physical Sciences
Regression Analysis
Female
medicine.symptom
Research Article
Imaging Techniques
Cerebrovascular Diseases
Neuroimaging
Hemorrhage
Linear Regression Analysis
Research and Analysis Methods
Statistics
Nonparametric
03 medical and health sciences
Signs and Symptoms
Diagnostic Medicine
Image Interpretation
Computer-Assisted
medicine
Humans
Statistical Methods
Aged
Cerebral Hemorrhage
Retrospective Studies
Intracerebral hemorrhage
Hemostasis
Fibrin
business.industry
lcsh:R
Biology and Life Sciences
Proteins
Retrospective cohort study
medicine.disease
Computed Axial Tomography
lcsh:Q
business
Tomography
X-Ray Computed
030217 neurology & neurosurgery
Mathematics
Follow-Up Studies
Neuroscience
Zdroj: PLoS ONE, Vol 13, Iss 10, p e0205436 (2018)
PLoS ONE
ISSN: 1932-6203
Popis: Background Clot retraction in intracerebral hemorrhage (ICH) has been described and postulated to be related to effective hemostasis and perihematoma edema (PHE) formation. The incidence and quantitative extent of hematoma retraction (HR) is unknown. Our aim was to determine the incidence of HR between baseline and time of admission. We also tested the hypothesis that patients with HR had higher PHE volume and good prognosis. Methods This was a retrospective single-centre study in which serial planimetric volume measurements of the total hematoma volume (parenchymal (IPH) and intraventricular (IVH)) and PHE were performed in ICH patients with baseline non-contrast computed tomography (CT) completed within 6 hours of onset and follow-up CT 24 (±12) hours from symptom onset. HR was defined as a decrease in volume of >3ml or >15%, and hematoma expansion (HE) as an increase of >6ml or >30%. All other patients were categorized as stable hematoma (HS). Good outcome was defined as modified Rankin Scale (mRS) 0–2 at 90 days. Results A total of 136 patients (mean age = 69.3±13.39 years, 58.1% male) were included. Median (interquartile range) baseline total hematoma volume was 14.96 (7.80, 31.88) ml. HR >3ml and >15% occurred in 6 (4.4%) and 8 (5.9%) patients, respectively. Neither definition of HR was associated with follow-up PHE (p>0.297) or good outcome (p>0.249). IVH was the only independent predictor of HR (p
Databáze: OpenAIRE
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