Surface structure of antral gastric mucosa represents the status of histologic gastritis: fundamental evidence for the evaluation of antral gastritis by magnifying endoscopy
| Autor: | Masanori Ito, Yasuo Egi, Sun Jin Kim, Shinji Tanaka, Hiroyuki Ueda, Ken Haruma, Kazuaki Chayama |
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| Rok vydání: | 2006 |
| Předmět: |
Male
medicine.medical_specialty Pathology Surface Properties H&E stain Gastroenterology Internal medicine Biopsy Gastroscopy medicine Gastric mucosa Surface structure Humans Antrum Hepatology medicine.diagnostic_test business.industry Magnifying endoscopy Middle Aged Endoscopy medicine.anatomical_structure Gastric Mucosa Gastritis Female medicine.symptom business |
| Zdroj: | Journal of gastroenterology and hepatology. 21(5) |
| ISSN: | 0815-9319 |
| Popis: | Background: Recent studies have demonstrated the diagnostic potential of magnifying endoscopy in cases of histologic gastritis. The aim of the present study was to clarify whether the mucosal surface structure reflects the degree of histologic gastritis below the surface. Methods: Gastric biopsy specimens were obtained from 1018 Japanese patients and were stained with hematoxylin and eosin. In 863 sections examined, gastritis was graded by means of the updated Sydney system, and the surface structure was classified as one of four types: flat, irregular, papillary, or non-structured. In addition, 103 patients underwent gastric examination by magnifying gastroscopy. Results: The surface structure of most biopsy sections with normal mucosa and no Helicobacter pylori infection was classified as the flat type. Grades of histological gastritis were statistically lower in flat-type sections than in other types. Histologic gastritis was found in 91% of sections with a non-flat surface structure. Helicobacter pylori infection was confirmed in 96% of these cases. Most biopsy sections in patients with abnormal magnifying endoscopy features were of the non-flat type and showed histologic gastritis. Conclusions: The surface structure of the gastric mucosa reflects the status of histologic gastritis. Magnifying gastroscopy could be a useful non-invasive method of diagnosing histologic gastritis. |
| Databáze: | OpenAIRE |
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