Ergosterol biosynthesis and its inhibition by fenpropimorph in Fusarium species
Autor: | Danièle Debieu, Jocelyne Bach, Pierre Leroux, Michel Gredt, Claude Gall, Christian Malosse |
---|---|
Přispěvatelé: | Unité de phytopharmacie et médiateurs chimiques, Institut National de la Recherche Agronomique (INRA), ProdInra, Migration |
Rok vydání: | 1992 |
Předmět: |
0106 biological sciences
Fusarium Plant Science Horticulture Reductase 01 natural sciences Biochemistry 03 medical and health sciences chemistry.chemical_compound Squalene Biosynthesis polycyclic compounds Molecular Biology [SDV.BV.PEP] Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacy ComputingMilieux_MISCELLANEOUS Mycelium 030304 developmental biology 0303 health sciences Fenpropimorph Ergosterol biology ACTIVITE ANTIFONGIQUE General Medicine biology.organism_classification Sterol [SDV.BV.PEP]Life Sciences [q-bio]/Vegetal Biology/Phytopathology and phytopharmacy chemistry lipids (amino acids peptides and proteins) 010606 plant biology & botany |
Zdroj: | Phytochemistry Phytochemistry, Elsevier, 1992, 31 (4), pp.1223-1233 |
ISSN: | 0031-9422 |
DOI: | 10.1016/0031-9422(92)80265-g |
Popis: | In the mycelium of all the Fusarium species studied, the major sterol was ergosterol in the absence of fenpropimorph. In the presence of this fungicide fenpropimorph-sensitive strains, with the exception of F. nivale , accumulated mainly Δ 8,14 -sterols and tolerant ones accumulated either both Δ 8,14 - and Δ 8 -sterols or only Δ 8 -sterols. This seemed to indicate that fenpropimorph toxicity was related to sterol Δ 14 -reductase sensitivity. In F. nivale , which was highly sensitive to fenpropimorph, the accumulation of only Δ 8 -sterols indicated that the main target enzyme was sterol Δ 8 →Δ 7 -isomerase. In addition to Δ 8,14 -and Δ 8 -sterols, squalene was accumulated in very high amounts in several strains; the level of squalene accumulation did not seem to be correlated with fenpropimorph sensitivity. |
Databáze: | OpenAIRE |
Externí odkaz: |