Combination of Deauville score and quantitative positron emission tomography parameters as a predictive tool of anti‐CD19 chimeric antigen receptor T‐cell efficacy

Autor:	Anna Guidetti, Anna Dodero, Alice Lorenzoni, Sara Pizzamiglio, Giovanni Argiroffi, Annalisa Chiappella, Filippo Bagnoli, Vincenzo Marasco, Cristiana Carniti, Chiara Monfrini, Ettore Seregni, Martina Pennisi, Paolo Verderio, Alessandra Alessi, Paolo Corradini
Rok vydání:	2022
Předmět:	Cancer Research Receptors Chimeric Antigen Lymphoma B-Cell T-Lymphocytes Prognosis Oncology Fluorodeoxyglucose F18 Positron-Emission Tomography Positron Emission Tomography Computed Tomography Humans Prospective Studies Lymphoma Large B-Cell Diffuse Neoplasm Recurrence Local Retrospective Studies
Zdroj:	Cancer. 129:255-263
ISSN:	1097-0142 0008-543X
DOI:	10.1002/cncr.34532
Popis:	Autologous anti-CD19 chimeric antigen receptor (CAR) T-cell therapy is an effective treatment for approximately 40% of relapsed/refractory large B cell lymphomas (LBCL), and early identification of patients at risk for relapse or progression after CAR T-cell therapy represents a clinical need.The authors conducted a single-center prospective study on 47 relapsed/refractory LBCL receiving CAR T-cell therapy to evaluate the prognostic value of baseline and after infusionDeep variation of standardized uptake value (SUV)PET parameters and association of DS and variation of SUVThis is a single-center prospective study on 47 lymphoma patients receiving commercial chimeric antigen receptor T-cell therapy aimed to evaluate the prognostic value of baseline and after infusion
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d17459f07376d47d811e32402d8bbbf https://doi.org/10.1002/cncr.34532 Zobrazit plný text záznamu Plný text