Myocarditis with Advanced Atrioventricular Block after Allogeneic Stem Cell Transplantation: A Case Report and Literature Review
| Autor: | Takehiko Kirihara, Hiroko Kazumoto, Kunihiko Shimizu, Masahiko Sumi, Mari Kitahara, Yuki Hiroshima, Hikaru Kobayashi, Keijiro Sato, Nozomu Uematsu, Toshimitsu Ueki, Tsutomu Shishido |
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| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Myocarditis Prednisolone Shock Cardiogenic Graft vs Host Disease Case Report 030204 cardiovascular system & hematology 03 medical and health sciences 0302 clinical medicine Maintenance therapy allogeneic stem cell transplantation atrioventricular block graft-versus-host disease Internal Medicine medicine Humans Glucocorticoids business.industry Cardiogenic shock General Medicine Middle Aged Precursor Cell Lymphoblastic Leukemia-Lymphoma medicine.disease Surgery Transplantation Graft-versus-host disease Female 030211 gastroenterology & hepatology Cord Blood Stem Cell Transplantation business Complication Atrioventricular block medicine.drug |
| Zdroj: | Internal Medicine |
| ISSN: | 1349-7235 0918-2918 |
| DOI: | 10.2169/internalmedicine.3322-19 |
| Popis: | A 51-year-old woman with Philadelphia chromosome-positive acute lymphoblastic leukemia underwent a second cord blood transplantation followed by maintenance therapy with interferon-α. After 33 months, she developed cardiogenic shock caused by advanced atrioventricular block. Laboratory tests revealed increased myocardium enzymes, and ultrasonic cardiography demonstrated mild thickening of the left ventricular wall. She was diagnosed with myocarditis and successfully treated using prednisolone. Myocarditis after allogeneic stem cell transplantation is a rare but potentially fatal complication. However, it is important for physicians to be aware of this complication because all of the symptoms may be reversed with immunosuppressive treatment. |
| Databáze: | OpenAIRE |
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