Impact of Negative Symptoms on Quality of Life in Patients with Schizophrenia
| Autor: | Diego Novick, Y Cheng, J.M. Haro, William Montgomery, V. Moneta |
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| Rok vydání: | 2015 |
| Předmět: |
Quality of life
medicine.medical_specialty Assistència ambulatòria business.industry Health Policy Schizophrenia (object-oriented programming) Public Health Environmental and Occupational Health Ambulatory medical care Data science Quality of life (healthcare) Text mining Qualitat de vida Schizophrenia Medicine In patient Esquizofrènia Antipsicòtics Antipsychotic drugs business Psychiatry |
| Zdroj: | Dipòsit Digital de la UB Universidad de Barcelona VALUE IN HEALTH r-FSJD: Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu Fundació Sant Joan de Déu r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu instname |
| ISSN: | 1098-3015 |
| Popis: | Objectives: The present study analyses the impact and influence of negative symptoms on quality of life (QoL). Methods: The W-SOHO study is a three year follow-up study on the outpatient care of schizophrenia that included 17,384 patients from 37 countries. Patients were recruited in W-SOHO by their treating psychiatrists when starting or changing antipsychotic medication. Evaluation was conducted during the normal course of care and was scheduled every six months after the baseline visit. The Clinical Global Impressions Severity Scale - Schizophrenia version (CGI-SCH) was used to assess symptom severity across overall, positive, negative, depressive and cognitive subdomains. Quality of life (QoL) was assessed using the EuroQOL 5-D questionnaire. Pearson correlation coefficients (PCC) were used to analyze the relationship between continuous variables. A mixed model with repeated measures (MMRM) was used to analyze the factors associated with quality of life during follow-up. Results: Quality of life at baseline was more highly correlated with negative symptoms than with positive symptoms (PCC -0.25 for positive symptoms and -0.29 for negative symptoms; p |
| Databáze: | OpenAIRE |
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