Steroid secretion by rat adrenal glands during the first week following adrenal enucleation
| Autor: | Margarethe Holzbauer, H. Traikov, A. F. De Nicola, Marion K. Birmingham, Urma Godden |
|---|---|
| Rok vydání: | 1972 |
| Předmět: |
Male
medicine.medical_specialty Time Factors medicine.medical_treatment Enucleation Biochemistry Steroid chemistry.chemical_compound Endocrinology Corticosterone Internal medicine Adrenal Glands medicine Animals Regeneration Secretion Desoxycorticosterone Progesterone Adrenal cortex Chemistry Regeneration (biology) Sodium Adrenalectomy Venous blood Rats medicine.anatomical_structure Pregnenolone Sodium retention |
| Zdroj: | Journal of Steroid Biochemistry. 3:767-772 |
| ISSN: | 0022-4731 |
| DOI: | 10.1016/0022-4731(72)90027-1 |
| Popis: | Adrenal venous blood was collected from rats 4 days after adrenal enucleation and from sham operated controls. The amount of regenerated cortical tissue was measured in serial sections of the glands. The newly regenerated adrenal cortex produced per unit adrenal tissue only about 14% of the amount of corticosterone and less than 12% of the amount of 18-OH-DOC secreted by the intact tissue, whereas the production of DOC was not decreased. The relative increase in the amount of DOC available to the rats bearing regenerating adrenal glands might contribute to the sodium retention observed in these rats during the first week after adrenal regeneration. |
| Databáze: | OpenAIRE |
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