Prenatal sex detection with endocervical smears: Successful results utilizing Y-body fluorescence
| Autor: | Catherine G. Palmer, Samuel A. Rhine, Robert E. Cleary, Joseph F. Thompson, Jeffrey L. Cain |
|---|---|
| Rok vydání: | 1975 |
| Předmět: |
Male
Sex Determination Analysis medicine.medical_specialty Pregnancy Trimester Third Cervix Uteri Y chromosome Pregnancy Prenatal Diagnosis Fetal sex Humans Medicine False Positive Reactions Vaginal Smears Gynecology Fetus Sex Chromosomes Staining and Labeling business.industry Obstetrics and Gynecology Pregnancy Trimester First Microscopy Fluorescence Karyotyping Pregnancy Trimester Second Female Sources of error business Endocervix |
| Zdroj: | American Journal of Obstetrics and Gynecology. 122:155-160 |
| ISSN: | 0002-9378 |
| DOI: | 10.1016/s0002-9378(16)33486-x |
| Popis: | Highly equivocal results, regarding procedures for the prenatal detection of fetal sex utilizing Y-body (Y chromosome) fluorescence in exfoliated interphase fetal cells found in the endocervix, are reported in the literature dating from 1971. The far-reaching genetic and obstetric implications of such procedures led us to investigate endocervical smears from 36 patients (taken during all three trimesters) and study the validity and practicality of this test. Fetal sex was correctly predicted in 31 of 36 cases and all 18 male predictions delivered males. In addition, many previously reported and newly found sources of error were encountered and evaluated. It is concluded that there are indeed cells of fetal origin being shed into the endocervix and they can be used as a reliable indicator of fetal sex in all three trimesters. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|