Estimating Fetal Age by Fetal Maternal Heart Rate Coupling Parameters
| Autor: | Raghad Al Sakaji, Ahsan H. Khandoker, Anita Krishnan, Kiyoe Funamoto, Yoshitaka Kimura, Maisam Wahbah |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
medicine.medical_specialty
Fetal Heart Rate Variability Gestational Age 030204 cardiovascular system & hematology Standard deviation Fetal Development 03 medical and health sciences Electrocardiography 0302 clinical medicine Fetal Heart Pregnancy Internal medicine Heart rate medicine Humans Bland–Altman plot Fetus 030219 obstetrics & reproductive medicine medicine.diagnostic_test business.industry Gestational age Heart Rate Fetal medicine.disease Cardiology Female business |
| Zdroj: | EMBC |
| ISSN: | 2694-0604 |
| Popis: | Beat-by-beat maternal and fetal heart couplings were reported to be evident throughout the fetal development. However, it is still unknown whether maternal-fetal heartbeat coupling parameters are associated with fetal development, and the potential interrelationships. Therefore, this study aims to investigate the associations of coupling parameters with fetal gestational age by multivariate regression models. Ten min abdominal lead-based maternal and fetal ECG signals were collected from 16 healthy pregnant women with healthy singleton pregnancies (19-32 weeks). Maternal and Fetal Heart Rate Variability (MHRV and FHRV) values as well as maternal-fetal heart rate coupling (strength, measured by A) parameters at various coupling ratios (associated with different Maternal:Fetal heartbeat ratios of 1:2, 1:3, 2:3, 2:4, 3:4, and 3:5) were calculated. Based on those features stepwise multivariate regression models were constructed by validating against the gold standard gestational age identified by crown-rump length from doppler echocardiogram. Among all models, the best model (Root Mean Square Error, RMSE=1.92) was found to be significantly (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|