Venous Thromboembolism During Pregnancy
| Autor: | Thomas E. Nolan, Marc R. Toglia |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
medicine.medical_specialty
medicine.drug_class Deep vein Pregnancy Complications Cardiovascular law.invention Randomized controlled trial Pregnancy law medicine Humans Intensive care medicine Fetus Labor Obstetric Heparin business.industry Anticoagulant Anticoagulants Obstetrics and Gynecology Puerperal Disorders General Medicine Thrombophlebitis medicine.disease Thrombosis Regimen medicine.anatomical_structure Female Pulmonary Embolism business medicine.drug |
| Zdroj: | Obstetrical & Gynecological Survey. 52:60-72 |
| ISSN: | 0029-7828 |
| Popis: | Pregnancy is widely recognized to be a physiologic state with a markedly elevated risk for thromboembolic complications. The diagnosis and management of venous thromboembolic events during pregnancy, however, remains controversial because of the lack of prospective, randomized trials that have included pregnant women. Significant progress has been made in the last 10 years in the management of these conditions in the nonpregnant patient and strong clinical guidelines have been established recently. Obstetrician-gynecologists may modify these guidelines and apply them to the pregnant patient based on their knowledge of the physiologic changes in pregnancy. Objective diagnostic techniques should be used liberally when the diagnosis of deep vein thrombosis or pulmonary emboli is considered because early intervention may prevent serious maternal sequelae including death. Heparin remains the anticoagulant of choice during pregnancy because of its proven safety for both the patient and the fetus. It is likely that long-term anticoagulation is necessary when venous thromboembolism occurs antepartum, although the most efficacious regimen has yet to be established. There is some concern about the prolonged use of heparin during pregnancy, particularly regarding the risk of osteopenia. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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