Ovarian tissue cryopreservation (OTC) in prepubertal girls and young women: an analysis of parents’ and patients’ decision-making
| Autor: | Clarisa R. Gracia, Chantae Sullivan-Pyke, Jeffrey S. Ginsberg, Claire A. Carlson, Maureen Prewitt |
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| Rok vydání: | 2017 |
| Předmět: |
Adult
Parents Infertility Adolescent media_common.quotation_subject Decision Making Fertility Profile of mood states 03 medical and health sciences 0302 clinical medicine Ovulation Induction Neoplasms Genetics Humans Medicine Ovarian tissue cryopreservation Fertility preservation Child Genetics (clinical) Oncofertility media_common Cryopreservation 030219 obstetrics & reproductive medicine business.industry Ovarian tissue Female infertility Ovary Fertility Preservation Obstetrics and Gynecology General Medicine Middle Aged medicine.disease Mood Reproductive Medicine 030220 oncology & carcinogenesis Child Preschool Female Tissue Preservation business Infertility Female Developmental Biology Clinical psychology |
| Zdroj: | Fertility and Sterility. 108:e187 |
| ISSN: | 0015-0282 |
| DOI: | 10.1016/j.fertnstert.2017.07.554 |
| Popis: | PURPOSE: The purpose of this study was to explore the decision-making influences, perceived level of control over decision-making, and mood states of parents and patients who were offered OTC prior to gonadotoxic therapy. METHODS: Parents and patients, at least 12 years old, who required gonadotoxic therapy and were offered OTC prior to therapy, were asked to complete questionnaires. Two validated instruments were also used: the Decision-Making Control Instrument (DMCI) and the Profile of Mood States (POMS). The factors that influenced decision-making were compared using Student’s t test, and the scores of DMCI and POMS were compared using the Mann-Whitney test. RESULTS: Thirty-six parents and 16 patients who elected ovarian tissue cryopreservation (OTC) completed questionnaires. Five parents who declined OTC also completed questionnaires. Accepters thought OTC was a good idea and that, in the future, science would enable cryopreserved ovarian tissue to be used to restore fertility (100% parents, 93.8% patients). Among accepters, the desire for genetically related children and prevention of the stress of infertility drove parents’ and patients’ decisions (90.9 and 100%, respectively). The desire to prevent the stress of infertility was important to parents, but patients were less likely to report that a desire to prevent the stress of infertility factored into their decision-making (66.7 vs. 50.0%; p |
| Databáze: | OpenAIRE |
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