Correlation between immunohistochemical expression of Ki-67and P63 and aggressiveness of urinary bladder urothelial carcinoma
| Autor: | Mohamed Selem, Mahmoud Ahmed Wahbbah, Sultan M Sultan, Mohamed M. Abdallah, Asmaa Gaber Abdou |
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| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty Urinary Bladder Urothelial Carcinoma Urinary system Clinical Biochemistry Immunology Urology Malignancy 01 natural sciences Biomarkers Tumor Humans Immunology and Allergy Medicine Prospective Studies Stage (cooking) Aged Urothelial carcinoma Aged 80 and over biology business.industry 010401 analytical chemistry Membrane Proteins Cancer Middle Aged medicine.disease Immunohistochemistry 0104 chemical sciences Medical Laboratory Technology Ki-67 Antigen Urinary Bladder Neoplasms Ki-67 biology.protein Female business |
| Zdroj: | Journal of Immunoassay and Immunochemistry. 42:188-201 |
| ISSN: | 1532-4230 1532-1819 |
| DOI: | 10.1080/15321819.2020.1844752 |
| Popis: | Urothelial carcinoma is the most common urinary malignancy with a wide proportion of cancer morbidity and mortality. The aim of the present study is to evaluate Ki-67 and p63 immunoexpression and their correlation with grade and stage of bladder urothelial carcinoma. Fifty cases of bladder urothelial carcinoma were investigated and were submitted to immunohistochemical staining for p63 and Ki-67, which were assessed qualitatively and quantitatively. A high percentage of p63 immunoexpression showed a significant association with low-grade tumors ( |
| Databáze: | OpenAIRE |
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