Lung growth index and lung growth ratio – new ultrasound parameters for predicting neonatal survival in fetuses with isolated left sided congenital diaphragmatic hernia?
Autor: | Michal Lipa, Miroslaw Wielgos, Przemyslaw Kosinski, Katarzyna Luterek |
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Rok vydání: | 2019 |
Předmět: |
Longest Diameter
030219 obstetrics & reproductive medicine Lung Receiver operating characteristic medicine.diagnostic_test business.industry Ultrasound Obstetrics and Gynecology Congenital diaphragmatic hernia Retrospective cohort study Balloon medicine.disease Fetoscopy 03 medical and health sciences 0302 clinical medicine medicine.anatomical_structure 030225 pediatrics Pediatrics Perinatology and Child Health medicine Nuclear medicine business |
DOI: | 10.6084/m9.figshare.7892438 |
Popis: | OBJECTIVE To evaluate the accuracy of several ultrasound parameters used to predict neonatal survival in fetuses with isolated left-sided severe congenital diaphragmatic hernia. This study is to compare different measurement methods. Also, two new ultrasound parameters have been described: the lung growth ratio (LGR) and the lung growth index (LGI). METHODS This was a retrospective study in pregnancies with a congenital diaphragmatic hernia (CDH) treated by fetoscopic tracheal occlusion (FETO). Pictures revealing four-chamber view of the fetal heart were reviewed and the right lung area was remeasured with several techniques: anterior-posterior, longest diameter, and tracing method. Based on the measurements, different parameters were obtained: lung-to-head ratio (LHR) (anterior-posterior), LHR (longest diameter), LHR (tracing method), o/e LHR (longest diameter), quantitative lung index (QLI) (longest diameter), and QLI (tracing method). All measurements were taken at the time of balloon insertion and at the time of balloon removal. In order to describe and compare fetal lung size indices in terms of their value as predictors of neonatal survival, receiver operating characteristic (ROC) analysis was applied. RESULTS Lung-to-head ratio calculated at the time of balloon occlusion measured with the tracing method reached the most significant statistical difference (p |
Databáze: | OpenAIRE |
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