| Popis: |
Here we review several factors involved in the emergence of antibiotic resistance. They are numerous, and the constant adaptation of microorganisms to the selective pressure exerted by antibiotics is extraordinary. The monitoring systems to assess antibiotic resistance levels and the extent of dissemination were highlighted. In addition, the success of spread of certain bacterial lineages and resistant mechanisms remains sometimes difficult to determine. The need to enlarge research in the area of antibiotic resistance was also stated, not only to better understand the dynamics of dissemination of resistance between different bacteria and different ecosystems, but also to enlarge the pharmaceutical pipeline of antibacterials against multidrug-resistant pathogens. It is manifest the severe consequences of antibiotic resistances to humans, animals and environment, constituting a global public health priority. In consequence, it should be tackled on all fronts in view to the essential concept of “One World-One Medicine-One Health”. info:eu-repo/semantics/publishedVersion |
