Cross-Sectional Surveys of Measles Antibodies in the Jiangsu Province of China from 2008 to 2010: The Effect of High Coverage with Two Doses of Measles Vaccine among Children
| Autor: | Zhiguo Wang, Pei Liu, Chengmei Jia, Xiaoyan Ding, Ying Hu, Xiuying Deng, Fubao Ma, Peishan Lu, Yuanbao Liu, Jie Min, Hong Tao, Haitao Yang |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Viral Diseases Epidemiology Cross-sectional study lcsh:Medicine Antibodies Viral Serology lcsh:Science Child Multidisciplinary Geography biology Data Collection Incidence (epidemiology) Aging and Immunity Middle Aged Viral Load Immunizations Infectious Diseases Child Preschool Medicine Female Public Health Research Article Adult China medicine.medical_specialty Adolescent Infectious Disease Control Measles Vaccine Immunology Measles Infectious Disease Epidemiology Herd immunity Measles virus Young Adult Age Distribution Environmental health medicine Humans Sex Distribution Biology Immunity to Infections Aged business.industry lcsh:R Immunity Infant biology.organism_classification medicine.disease Virology Cross-Sectional Studies lcsh:Q Preventive Medicine Measles vaccine business |
| Zdroj: | PLoS ONE PLoS ONE, Vol 8, Iss 6, p e66771 (2013) |
| ISSN: | 1932-6203 |
| DOI: | 10.1371/journal.pone.0066771 |
| Popis: | BACKGROUND: Changes in the epidemiological characteristics of measles since 2007 appeared in the Jiangsu province. Although the reported coverage with two doses of measles vaccine was greater than 95% in most regions of the province, measles incidence remained high across the whole province. Cross-sectional serological surveys of measles antibodies in the Jiangsu province of China were conducted from 2008 to 2010 to assess and track population immunity. METHODS: Measles-specific IgG levels were measured in serum samples using ELISA. GMTs and seroprevalence with 95% CIs were calculated by region, gender, and age. ANOVA and χ(2) tests were used to test for statistically significant differences between groups for GMT levels and seroprevalence, respectively. RESULTS: Seroprevalence showed a significantly increasing trend annually (CMH χ(2) = 40.32, p |
| Databáze: | OpenAIRE |
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