Scalable biocatalytic C–H oxyfunctionalization reactions

Autor:	Alison R. H. Narayan, Jonathan C Perkins, Ye Wang, Suman Chakrabarty
Rok vydání:	2020
Předmět:	Small Molecule Libraries Cytochrome P-450 Enzyme System Molecular Structure Chemistry Biocatalysis Oxygenases Nanotechnology General Chemistry Article
Zdroj:	Chem Soc Rev
ISSN:	1460-4744 0306-0012
DOI:	10.1039/d0cs00440e
Popis:	Catalytic C–H oxyfunctionalization reactions have garnered significant attention in recent years with their ability to streamline synthetic routes toward complex molecules. Consequently, there have been significant strides in the design and development of catalysts that enable diversification through C–H functionalization reactions. Enzymatic C–H oxygenation reactions are often complementary to small molecule based synthetic approaches, providing a powerful tool when deployable on preparative-scale. This review highlights key advances in scalable biocatalytic C–H oxyfunctionalization reactions developed within the past decade.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ce589bd5df52a41cc4a3da17a195d37 https://doi.org/10.1039/d0cs00440e Zobrazit plný text záznamu