Antenatal Glucocorticoids Reduce the Incidence of Refractory Hypotension in Low Birthweight Infants during the Early Neonatal Period, but Do Not Affect It beyond This Time
Autor: | Fusako Niwa, Masahiko Kawai, Kougoro Iwanaga, Hiroko Tomotaki, Seiichi Tomotaki, Shintaro Hanaoka, Takashi Matsukura |
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Rok vydání: | 2020 |
Předmět: |
Male
Pediatrics medicine.medical_specialty Vlbw infants Gestational Age Infant Premature Diseases Affect (psychology) Betamethasone 03 medical and health sciences 0302 clinical medicine Japan Humans Infant Very Low Birth Weight Medicine Glucocorticoids Retrospective Studies 030219 obstetrics & reproductive medicine business.industry Incidence Incidence (epidemiology) Significant difference Infant Newborn Obstetrics and Gynecology Gestational age Prenatal Care Early neonatal period Refractory hypotension Treatment Outcome Pediatrics Perinatology and Child Health Female Hypotension business Infant Premature |
Zdroj: | American Journal of Perinatology. 38:1057-1061 |
ISSN: | 1098-8785 0735-1631 |
DOI: | 10.1055/s-0040-1701608 |
Popis: | Objective This study aimed to clarify the effect of antenatal glucocorticoids (AGs) on the incidence of refractory hypotension (RH) in very low birthweight (VLBW) infants after the first week of life.Study Design We included VLBW infants born at a gestational age of Results A total of 115 infants were enrolled. The incidence of RH in the first week of life was significantly lower in the complete group than in the other groups. However, there was no significant difference in the incidence of RH after the first week of life among the groups.Conclusion AGs contribute to circulatory stabilization during the first week of life, but this effect does not last after 1 or 2 weeks of administration. In infants who receive AGs, physicians should consider that the risk of RH after the first week of life is not low. |
Databáze: | OpenAIRE |
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