Antenatal Glucocorticoids Reduce the Incidence of Refractory Hypotension in Low Birthweight Infants during the Early Neonatal Period, but Do Not Affect It beyond This Time

Autor: Fusako Niwa, Masahiko Kawai, Kougoro Iwanaga, Hiroko Tomotaki, Seiichi Tomotaki, Shintaro Hanaoka, Takashi Matsukura
Rok vydání: 2020
Předmět:
Zdroj: American Journal of Perinatology. 38:1057-1061
ISSN: 1098-8785
0735-1631
DOI: 10.1055/s-0040-1701608
Popis: Objective This study aimed to clarify the effect of antenatal glucocorticoids (AGs) on the incidence of refractory hypotension (RH) in very low birthweight (VLBW) infants after the first week of life.Study Design We included VLBW infants born at a gestational age of Results A total of 115 infants were enrolled. The incidence of RH in the first week of life was significantly lower in the complete group than in the other groups. However, there was no significant difference in the incidence of RH after the first week of life among the groups.Conclusion AGs contribute to circulatory stabilization during the first week of life, but this effect does not last after 1 or 2 weeks of administration. In infants who receive AGs, physicians should consider that the risk of RH after the first week of life is not low.
Databáze: OpenAIRE