Doctor shopping for methylphenidate as a proxy for misuse and potential abuse in the 67 million inhabitants in France
| Autor: | Vincent Pradel, Elisabeth Frauger, Thomas Soeiro, Joëlle Micallef |
|---|---|
| Přispěvatelé: | Institut de Neurosciences des Systèmes (INS), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM) |
| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: |
Adult
Male medicine.medical_specialty Adolescent Population MEDLINE 030226 pharmacology & pharmacy Proxy (climate) Young Adult 03 medical and health sciences 0302 clinical medicine Physicians medicine High doses Humans Pharmacology (medical) Prospective Studies Claims database Practice Patterns Physicians' Medical prescription Proxy (statistics) Psychiatry education Prescription Drug Misuse ComputingMilieux_MISCELLANEOUS Pharmacology education.field_of_study Doctor shopping business.industry Methylphenidate [SCCO.NEUR]Cognitive science/Neuroscience Middle Aged Opioid-Related Disorders Cross-Sectional Studies Female France business 030217 neurology & neurosurgery medicine.drug |
| Zdroj: | Fundamental & Clinical Pharmacology Fundamental & Clinical Pharmacology, Wiley, 2021, 35 (4), pp.751-761. ⟨10.1111/fcp.12612⟩ |
| ISSN: | 0767-3981 1472-8206 |
| Popis: | Doctor shopping enables subjects to receive more than the prescribed dose out of any medical management, which suggests a search for high doses and makes doctor shopping a relevant proxy for misuse and potential abuse. Therefore, this study aimed to identify and characterize profiles of subjects with doctor-shopping behavior for methylphenidate in the entire French population. This study is a cross-sectional study of doctor-shopping behavior for methylphenidate in France, in 2016, using the Systeme national des donnees de sante, and accounting for overlapping prescriptions. Subjects who obtained >840 mg by doctor shopping were defined as subjects with heavy doctor-shopping behavior, and subjects who obtained >0 mg and ≤840 mg by doctor shopping were defined as subjects with light doctor-shopping behavior. A total of 63 739 subjects were included, and received 339.6 kg of methylphenidate. Among them, 216 (0.3%) subjects had heavy doctor-shopping behavior, and 313 (0.5%) subjects had light doctor-shopping behavior. Compared with subjects with light doctor-shopping behavior, subjects with heavy doctor-shopping behavior were older (64% of 30- to 49-year-old subjects vs. 77% of ≤17-year-old subjects; P |
| Databáze: | OpenAIRE |
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