Transmitting the message: intracellular mRNA localization
| Autor: | Ilan Davis, Carine Meignin |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2010 |
| Předmět: |
Regulation of gene expression
ved/biology Mechanism (biology) ved/biology.organism_classification_rank.species Gene Expression Regulation Developmental Biological Transport Cell Biology Intracellular mRNA localization Biology Cell biology Synapse Protein Biosynthesis Translational regulation Protein biosynthesis Animals RNA Messenger Model organism Function (biology) Signal Transduction |
| Zdroj: | Current opinion in cell biology. 22(1) |
| ISSN: | 1879-0410 0955-0674 |
| Popis: | The intracellular localization of mRNA is an important mechanism for targeting proteins to their sites of function. Localized transcripts play key roles ranging from body axis determination to synapse plasticity, and recent studies highlight how common localized transcripts are in a variety of model organisms. In this review, we consider the full range of known mechanisms for delivering transcripts and anchoring them at their site of function. Finally, we evaluate the progress that has been made in the nervous system in understanding the mechanism and function of mRNA localization and translation regulation. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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