Seven challenges for modelling indirect transmission: Vector-borne diseases, macroparasites and neglected tropical diseases

Autor: Valerie Isham, T. Déirdre Hollingsworth, Alun L. Lloyd, Sebastian Funk, James E. Truscott, Juliet R. C. Pulliam
Rok vydání: 2015
Předmět:
Disease reservoir
qw_700
Epidemiology
Disease
Disease Vectors
0302 clinical medicine
Risk Factors
RA0421
FOI
force of infection
VBD
vector-borne disease
QA
EIR
entomological inoculation rate
Neglected tropical diseases
0303 health sciences
Transmission (medicine)
Incidence
Neglected Diseases
Vectors
Macroparasites
Infectious Diseases
Risk analysis (engineering)
NTD
neglected tropical disease
Indirect Transmission
030231 tropical medicine
wa_395
Biology
Microbiology
Article
wa_110
lcsh:Infectious and parasitic diseases
03 medical and health sciences
qx_200
Helminths
Virology
Vector-borne disease
Disease Transmission
Infectious
Parasitic Diseases
Animals
Humans
lcsh:RC109-216
Disease Reservoirs
030304 developmental biology
Models
Statistical
Public Health
Environmental and Occupational Health
M&E
monitoring and evaluation
Life stage
EIP
extrinsic incubation period
VC
vectorial capacity
Vector (epidemiology)
Immunology
Macroparasite
Parasitology
Zdroj: Epidemics, Vol 10, Iss C, Pp 16-20 (2015)
Epidemics
ISSN: 1755-4365
DOI: 10.1016/j.epidem.2014.08.007
Popis: Many of the challenges which face modellers of directly transmitted pathogens also arise when modelling the epidemiology of pathogens with indirect transmission – whether through environmental stages, vectors, intermediate hosts or multiple hosts. In particular, understanding the roles of different hosts, how to measure contact and infection patterns, heterogeneities in contact rates, and the dynamics close to elimination are all relevant challenges, regardless of the mode of transmission. However, there remain a number of challenges that are specific and unique to modelling vector-borne diseases and macroparasites. Moreover, many of the neglected tropical diseases which are currently targeted for control and elimination are vector-borne, macroparasitic, or both, and so this article includes challenges which will assist in accelerating the control of these high-burden diseases. Here, we discuss the challenges of indirect measures of infection in humans, whether through vectors or transmission life stages and in estimating the contribution of different host groups to transmission. We also discuss the issues of “evolution-proof” interventions against vector-borne disease.
Databáze: OpenAIRE
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