Long-term histopathologic and morphologic changes after thermal endometrial ablation
| Autor: | Ersadik Turan, Murat Inal, Hakan Postaci, Enver Vardar, Omur Taskin, Salih Sadik, A Onoglu, James M. Wheeler |
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| Rok vydání: | 2002 |
| Předmět: |
Adult
medicine.medical_specialty Pathology medicine.medical_treatment Tissue Adhesions Hysteroscopy Endometrium Atrophy Fibrosis medicine Electrocoagulation Humans Longitudinal Studies Prospective Studies Prospective cohort study Uterine Diseases medicine.diagnostic_test business.industry Thermal endometrial ablation Obstetrics and Gynecology Middle Aged medicine.disease Ablation Second-Look Surgery Endometrial ablation Female Radiology business Endometrial biopsy |
| Zdroj: | The Journal of the American Association of Gynecologic Laparoscopists. 9(2) |
| ISSN: | 1074-3804 |
| Popis: | Study Objective To outline long-term histologic features of endometrial ablation. Design Prospective longitudinal study (Canadian Task Force classification II-3). Setting Tertiary-care teaching hospital. Patients Twenty-six patients. Intervention Thermal ablation followed by second-look office hysteroscopy with endometrial biopsy. Measurements and Main Results Mean follow-up time to second-look hysteroscopy after ablation was 33.4 ± 2,1 months. Complete atrophy, partial adhesions or obliteration of the cavity, and fibrosis were observed at second-look hysteroscopy. Whereas all random biopsies were normal before ablation, biopsies after ablation revealed diminished endometrial glands with necrosis and scarring. The number of endometrial glands was not correlated with amount of bleeding or menstrual pattern. No premalignant or malignant lesions were found after ablation. Conclusion Although efficacy of endometrial ablation is related to initial thermal destruction and correlated with postablation hysteroscopic and histologic findings, endometrial regrowth is an expected development, not a failure of ablation. |
| Databáze: | OpenAIRE |
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