Velocity of coronary sinus blood flow as an indicator of coronary arterial flow

Autor: Henry S. Badeer, Paul D. Stein, Allen E. Zencka, William H. Schuette
Rok vydání: 1970
Předmět:
Zdroj: American heart journal. 80(2)
ISSN: 0002-8703
Popis: In order to determine the validity of coronary sinus mean blood velocity as an indicator of coronary arterial mean blood flow, comparisons were made of the effects of various interventions upon coronary sinus velocity and left anterior descending coronary arterial flow. Velocity in the coronary sinus was measured with a cathetertip electromagnetic transducer. Flow in the left anterior descending coronary artery was measured simultaneously with a cuff electromagnetic flow transducer. Forty-two observations of the effects of norepinephrine, isoproterenol, and asphyxia were made in seven dogs under pentobarbital anesthesia. Coronary sinus mean velocity increased nearly in direct proportion to increments of left anterior descending mean flow following norepinephrine, isoproterenol, and asphyxia. As would be expected, increments in coronary sinus velocity were linearly related, but were smaller than the increments in left anterior descending flow during reactive hyperemia of the left anterior descending coronary artery. Coronary sinus velocity qualitatively reflected changes of left anterior descending flow, but did not reliably quantitate these changes following nitroglycerin. The results of this study indicate that coronary sinus blood velocity is a fairly reliable indicator of changes of coronary arterial flow. It can be utilized under rapidly changing conditions and monitored continuously over long periods. The method requires no major surgery and would seem to be potentially applicable to human subjects.
Databáze: OpenAIRE