Clinicopathologic Features of Colorectal Polyps in Shahid Beheshti University of Medical Sciences (SBMU)

Autor: Hamid Mohaghegh Shalmani, Arsham Moradi, Zeinab Kishani Farahani, Arash Dehgan, Abolfazl Movafagh, Mohammad Hassan Heidari, Roxana Boran, Mahsa Ahadi, Afshin Moradi, Behrang Kazemi Nejad, Amir Sadeghi, Elena Jamali, Azadeh Rakhshan, Tahmineh Mollasharifi, Maliheh Saberi Afsharian
Rok vydání: 2018
Předmět:
0301 basic medicine
Male
Adenomatous polyps
Iran
Gastroenterology
0302 clinical medicine
Risk groups
Villous Pattern
Aged
80 and over
Medical record
Incidence
General Medicine
Colonoscopy
Middle Aged
Prognosis
serrated polyps
surgical procedures
operative
030220 oncology & carcinogenesis
adenomatous polyps
Female
Colorectal Neoplasms
Research Article
Adenoma
Adult
Colorectal polyps
medicine.medical_specialty
Adolescent
Universities
Colonic Polyps
digestive system
Shahid
03 medical and health sciences
Young Adult
Internal medicine
medicine
otorhinolaryngologic diseases
Humans
neoplasms
Aged
Retrospective Studies
business.industry
Retrospective cohort study
Histology
Odds ratio
digestive system diseases
non-neoplastic polyps
030104 developmental biology
business
Precancerous Conditions
Follow-Up Studies
Zdroj: Asian Pacific Journal of Cancer Prevention : APJCP
ISSN: 2476-762X
Popis: Aim: This study was designed to report epidemiologic findings of polyps in Iranian patients, and predict histology of polyp regarding to demographic and colonoscopic findings. Background: Classification of colorectal polyps had been revised in the past two decades and there is a need for polyp categorization in the Iranian Health System. Patients and methods: In this retrospective study, the medical records of patients with colonoscopic diagnosis of polyp in pathology departments of SBMU affiliated teaching hospitals were reviewed. Patient’s slides evaluated and demographics findings were assessed. The anatomical location, macroscopic appearance including size and histological assessment of all polyps were recorded. Results: From total number of 1106 polyps (detected in 862 patients), adenomatous polyps (638 [57.7%]) were the most prevalent findings, followed by colon mucosal tag (184[16.6%]), hyperplastic and serrated polyps (122[11%]), inflammatory polyps (110[9.9%]), hamartomatous (21[1.9%]), and malignant lesions (13[1.2%]). Multivariate logistic regression showed age (each one year increasing age; odds ratio [OR] = 1.026, 95%confidence interval [CI] = 1.016–1.036, p < 0.0001), location of polyp (right colon; OR = 1.905, 95%CI = 1.366–2.656, p < 0.0001), and polyp size of 5-10 mm (OR = 1.662, 95%CI = 1.214–2.276, p = 0.002), and polyp size of >10 mm (OR = 2.778, 95%CI = 1.750–4.411, p< 0.0001) were independently associated with neoplastic polyps. Also, polyp size of >10 mm (OR= 2.613, 95%CI= 1.083-6.307, p=0.033), tubulovillous pattern of polyp (OR= 3.508, 95%CI= 1.666-7.387, p=0.001) and villous pattern of polyp (OR= 10.444, 95%CI= 4.211-25.905, p
Databáze: OpenAIRE
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