A long-term study and correlation of lymphocyte and neutrophil function in the patient with burns
| Autor: | Nagy H, Palkert D, Alexander Jw, Glenn D. Warden, Cora K. Ogle, Carey M, Sandra L. Wood, James D. Ogle |
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| Rok vydání: | 1990 |
| Předmět: |
Adult
Male Burn injury Blood Bactericidal Activity Staphylococcus aureus Time Factors Adolescent Neutrophils Lymphocyte Lymphocyte proliferation medicine.disease_cause Lymphocyte Activation chemistry.chemical_compound Superoxides Escherichia coli Medicine Humans In patient Lymphocytes Child General Nursing Thermal injury business.industry Rehabilitation Zymosan Infant Bacterial Infections Middle Aged Long term learning medicine.anatomical_structure chemistry Child Preschool General Health Professions Immunology Emergency Medicine Surgery Female business Burns |
| Zdroj: | The Journal of burn carerehabilitation. 11(2) |
| ISSN: | 0273-8481 |
| Popis: | Twenty-five patients were studied to determine the effects of thermal injury on neutrophil bactericidal function and superoxide release and on lymphocyte proliferation. Neutrophils in patients with burns had depressed killing of Staphylococcus aureus for more than 150 days after burn injury, but killing of Escherichia coli returned to normal. FMLP-stimulated superoxide release by neutrophils in patients with burns was depressed for over 100 days after burn injury, whereas superoxide release by neutrophils in patients with burns stimulated with serum-opsonized zymosan was depressed for 42 days after burn injury. In patients with burns lymphocyte proliferation, with phytohemagglutinin as a mitogen, was suppressed for up to 85 days after injury, then returned to normal. The mixed lymphocyte response was suppressed up to 170 days after injury. |
| Databáze: | OpenAIRE |
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